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Articles by Van Cleemput
CD4-directed nanoblades enable selective genome editing in CD4 + cells and HIV suppression in vitro and in vivo
Reagents and tools table Reagent/resource Reference or source Identifier or catalog number Experimental models: Cell lines HEK293T cells ATCC CRL-3216 TZM-bl cells NIH HIV Reagent Program ARP-8129 J-Lat 10.6 cells NIH HIV Reagent Program ARP-9849 CD4+ eGFP- Sup-T1 cells ATCC CRL-1942 CD4- eGFP- Sup-T1 cells This study N/A CD4+ eGFP+ Sup-T1 cells This study N/A CD4- eGFP+ Sup-T1 cells This study N/A Experimental models: Organisms/strains Mouse: NSG-SGM3 The Jackson Laboratory JAX: 013062...
Transdisciplinary training to address challenges in genomic epidemiology of infectious diseases
1 Introduction Genomic epidemiology of infectious disease has experienced a large shift in prominence and importance over the last couple of years, fueled by the COVID-19 pandemic and the rapid expansion of capacity for pathogen genomic sequencing and analysis. At its core, the field focuses on using viral or bacterial genome sequences to characterize an underlying pathogen population, tracing its evolution and transmission dynamics (1–3).
[2308.02540] Top-down Automated Theorem Proving (Notes for Sir Timothy)
We describe a "top down" approach for automated theorem proving (ATP). Researchers might usefully investigate the forms of the theorems mathematicians use in practice, carefully examine how they differ and are proved in practice, and code all relevant domain concepts. These concepts encode a large portion of the knowledge in any domain.
Organ-specific genome diversity of replication-competent SARS-CoV-2 - Nature Communications
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is not always confined to the respiratory system, as it impacts people on a broad clinical spectrum from asymptomatic to severe systemic manifestations resulting in death. Further, accumulation of intra-host single nucleotide variants during prolonged SARS-CoV-2 infection may lead to emergence of variants of concern (VOCs). Still, information on virus infectivity and intra-host evolution across organs is sparse.
[2011.11576] Conjecturing-Based Discovery of Patterns in Data
[Submitted on 23 Nov 2020 ( v1 ), last revised 14 Jul 2023 (this version, v4)] Title:Conjecturing-Based Discovery of Patterns in Data Download a PDF of the paper titled Conjecturing-Based Discovery of Patterns in Data, by J.P. Brooks and D.J. Edwards and C.E. Larson and N.
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