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Articles by van Hilst
The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial
Splenectomy is the current standard during left-sided pancreatectomy for pancreatic ductal adenocarcinoma (PDAC) with the goal to perform adequate lymphadenectomy in the splenic hilum. The added value of splenectomy regarding resection of involved lymph nodes (LNs) and survival benefit has not been confirmed. Moreover, asplenia holds severe risks, including the high mortality risk of overwhelming post-splenectomy sepsis (50–70%)1.
Early experience with robotic pancreatoduodenectomy versus open pancreatoduodenectomy: nationwide propensity-score-matched analysis
Pancreatoduodenectomy (PD) is a complex procedure associated with a high risk of postoperative complications. Robotic pancreatoduodenectomy (RPD) has gained popularity based on reports from a few experienced, very high-volume centres1–3. RPD aims to reduce surgical trauma compared with open pancreatoduodenectomy (OPD) and hence could improve short- and long-term outcomes. However, some studies have reported safety concerns regarding the implementation of RPD into clinical practice4–6.
The clinical implication of minimally invasive versus open pancreatoduodenectomy for non-pancreatic periampullary cancer: a systematic review and individual patient data meta-analysis (pdf) | Paperity
Langenbeck's Archives of Surgery, Aug 2023 Most studies on minimally invasive pancreatoduodenectomy (MIPD) combine patients with pancreatic and periampullary cancers even though there is substantial heterogeneity between these tumors. Therefore, this study aimed to evaluate the role of MIPD compared to open pancreatoduodenectomy (OPD) in patients with non-pancreatic periampullary cancer (NPPC).
Teaching modern pancreatic surgery: close relationship between centralization, innovation, and dissemination of care
Pancreatic surgery is a low-volume, but high-complexity, field, with a daunting learning curve and challenging morbidity from an individual and system level. Pancreatoduodenectomy (PD) is still burdened by 20 per cent major morbidity, 12 per cent failure to rescue (FTR), and 2 per cent in-hospital mortality rates at tertiary referral centres1.
Minimally invasive versus open pancreatoduodenectomy for pancreatic and peri-ampullary neoplasm (DIPLOMA-2): study protocol for an international multicenter patient-blinded randomized controlled trial | Trials | Full Text
References Gagner M, Pomp A. Laparoscopic pylorus-preserving pancreatoduodenectomy. Surg Endosc. 1994;8(5):408–10. Article CAS PubMed Google Scholar Kendrick ML. Laparoscopic and robotic resection for pancreatic cancer. Cancer J. 2012;18(6):571–6. Article PubMed Google Scholar Giulianotti PC, et al. Robotics in general surgery: personal experience in a large community hospital. Arch Surg. 2003;138(7):777–84. Article PubMed Google Scholar Poves, I., et al.
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