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Articles by Van Oosterom
Neutrophils suppress adaptive αβ T cells but not the innate γδ T cells and natural killer cells
Abstract The presence of polymorphonuclear neutrophils (PMNs) in the tumor microenvironment is associated with lower survival rates for cancer patients. Presumably due to the immunosuppressive activity of neutrophils (also known as Myeloid-Derived Suppressor Cell (MDSC) activity). We investigated whether this MDSC activity shows any selectivity in suppressing specific lymphocyte subsets. Our data show that CD4+ and CD8+ T cells, both naive and memory fractions, are sensitive to PMN-MDSC activity.
Identification of immunosuppressive neutrophils using multi-omics: why functional testing remains key
Abstract Polymorphonuclear neutrophils (PMNs) are innate cells that may act as myeloid-derived suppressor cells (MDSCs), most often characterized by their immunosuppressive capacity towards immune cells within the tumor microenvironment.
High-Altitude Exposure and Diabetic Retinopathy: Unveiling the Impact and Mechanisms of Alleviation
Keywords: High altitude, Diabetic retinopathy, Diabetes mellitus High altitude (HA) poses numerous challenges for individuals, with over 400 million people (7% of the world’s population) permanently residing above 1,500 m [1]. Notably, approximately 42.3% of Tibetans in China and a significant population from the Andes live at altitudes exceeding 3,500 m [2, 3].
Generalizing Simultaneously to Support Smooth Zooming: Case Study of Merging Area Objects
Journal of Geovisualization and Spatial Analysis, May 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s41651-022-00109-x.pdf Peng, Dongliang, Meijers, Martijn, van Oosterom, Peter. , Journal of Geovisualization and Spatial Analysis, 2023, pp. 1-19, Volume 7, Issue 1, DOI: 10.1007/s41651-022-00109-x
Comparison of two hybrid sentinel node tracers: indocyanine green (ICG)-99mTc-nanocolloid vs. ICG-99mTc-nanoscan from a nuclear medicine and surgical perspective (pdf) | Paperity
European Journal of Nuclear Medicine and Molecular Imaging, Mar 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s00259-023-06157-9.pdf Vreeburg, Manon T. A., Azargoshasb, Samaneh, van Willigen, Danny, Molenaar, Tom, van Oosterom, Matthias N., Buckle, Tessa, Slof, Leon J., Klop, Martin, Karakullukcu, Baris, Donswijk, Maarten, van der Poel, Henk G., van Leeuwen, Fijs W. B., Brouwer, Oscar R., Rietbergen, Daphne D. D..
Modeling adaptation of sorghum in Ethiopia with APSIM-opportunities with G×E×M
Agronomy for Sustainable Development, Jan 2023 This is a preview of a remote PDF: https://link.springer.com/content/pdf/10.1007/s13593-023-00869-w.pdf Tirfessa, Alemu, Getachew, Fikadu, McLean, Greg, van Oosterom, Erik, Jordan, David, Hammer, Graeme. , Agronomy for Sustainable Development, 2023, pp. 1-13, Volume 43, Issue 1, DOI: 10.1007/s13593-023-00869-w
Environmental Enrichment Mitigates Age-Related Metabolic Decline and Lewis Lung Carcinoma Growth in Aged Female Mice
Skip Nav Destination Research Articles| December 01 2021
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