1. Introduction Enteroviruses (EV) are a major cause of acute viral illness worldwide (1), typically resulting in mild symptoms that are usually self-limited in children and rarely lead to long-term complications. In newborns younger than 28 days (neonates), the clinical course is rather heterogeneous, ranging from asymptomatic infection to severe, life-threatening disease with manifestations such as sepsis, myocarditis, hepatitis, coagulopathy, pneumonia, and meningoencephalitis (2–6).
