Biophysical analysis of gelatin and PLGA nanoparticle interactions with complex biomimetic lung surfactant models† W. Daear, ‡a K. Sule, ‡a P. Lai §a and E. J. Prenner *a Abstract Biocompatible materials are increasingly used for pulmonary drug delivery, and it is essential to understand their potential impact on the respiratory system, notably their effect on lung surfactant, a monolayer of lipids and proteins, responsible for preventing alveolar collapse during breathing cycles.
