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Articles by W. Klapper
Cyclin D1 rearranged diffuse large B-cell lymphoma—an evolving concept - Leukemia
Abstract Rearrangement of Cyclin D1 (CCND1-R) is the hallmark genetic lesion of mantle cell lymphoma (MCL). However, recently diffuse large B-cell lymphomas (DLBCL) have been described carrying a CCND1-R, often with additional rearrangements of BCL2, BCL6 and/or MYC raising the question if these are bona fide DLBCL or pleomorphic MCL.
Correction to: Leukemia https://doi.org/10.1038/s41375-025-02567-w, published online 24 March 2025 In this article the author’s name D. A. Eichenauer. was incorrectly written as D. Eichenauer. The original article has been corrected. Additional information The original article can be found online at https://doi.org/10.1038/s41375-025-02567-w.
Correlation of progression-free survival and overall survival after treatment for relapsed Hodgkin lymphoma: individual patient data analysis of randomized German Hodgkin Study Group (GHSG) Trials | Leukemia
To the Editor: Progression-free survival (PFS) and overall survival (OS) are key indicators of treatment success in Hodgkin lymphoma (HL), both in the context of first-line treatment and in relapsed HL. While OS is often prioritized by regulatory authorities and health technology assessment bodies [1], PFS is highly relevant to patients and frequently serves as primary endpoint in clinical research [2].
Reply to the letter to the editor ‘the clinical dilemma of grade 3 follicular lymphoma’ by Sorigue et al.
As pointed out by Sorigue et al. [1] in their letter related to our work [2], follicular lymphoma (FL) grade 3A and 3B is managed in Europe to some extent differently to China and the United States. In their letter, Sorigue et al. emphasize that this setting of clinical borders is not evidence-based. We agree with this comment and like to add that these treatment recommendations were developed from historical classifications before the WHO classification in 2001 implemented grading of FL.
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