In The Know Woman captures touching moment her sister with Down syndrome goes on date A jewelry designer’s TikTok has gone viral for chronicling the relationship between her sister and the latter’s boyfriend, both of whom have Down syndrome. Together, Tiffany McDowell and Mallory Snellen, who has Down syndrome, run Mallory Paige Designs, a small jewelry shop in Trinity, N.C. For the past year, McDowell has been documenting their sisterly relationship on the social media platform.