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Abstract Cystitis is a common urinary system disease in women. However, there are currently no effective treatment options except antibiotics. Therefore, establishing an effective and stable animal model is helpful for further study of cystitis.
A newly isolated intestinal bacterium involved in C-ring cleavage of flavan-3-ol monomers and antioxidant activity of the metabolites Flavan-3-ols are an important class of secondary metabolites in many plants. Its bioavailability and bioactivity are largely determined by the metabolism of intestinal microbiota. However, little is known about the intestinal bacteria involved in the metabolism of flavan-3-ols and the activities of its metabolites.
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessCommunication by , , and * Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization (MARA), Guangdong Province Key Laboratory of Tropical and Subtropical Fruit Tree Research, Institute of Fruit Tree Research, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China * Author to whom correspondence should be addressed.
Procyanidin A1 and its digestive products prevent acrylamide-induced intestinal barrier dysfunction via the MAPK-mediated MLCK pathway Procyanidins can alleviate small intestine damage induced by acrylamide (ACR). However, little is known about whether procyanidins after gastrointestinal digestion can prevent ACR-induced intestinal barrier damage and the possible mechanism.
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