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Abstract: Objective To establish a mouse model of aorta dissection (AD) by β-aminopropionitrile (BAPN) in drinking water + subcutaneously pumped angiotensin Ⅱ (Ang Ⅱ) infusion. Methods Forty 3-week-old C57B1/6J male mice were randomly divided into two groups. All animals received 0.1 g/kg/d BAPN in drinking water for 4 weeks.
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