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Abstract Purpose: Observational associations between statin exposure and mortality in sepsis may be distorted by immortal time bias and covariate timing. We reassessed this association using time-updated exposure and complementary landmark analyses in MIMIC-IV. Methods: Adults with sepsis in MIMIC-IV version 3.1 were followed from ICU admission for 28-day all-cause mortality.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.