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Weili Pan

As seen in: Atherosclerosis, International Journal of Cardiology
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Articles by Weili Pan

Plasma ceramides are associated with coronary atherosclerotic burden in patients with ST-segment elevation myocardial infarction

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By Weili Pan, Chinese Ministry, Province Heilongjiang, Longyan Li
| International Journal of Cardiology Verified
Highlights • The study firstly related plasma ceramides to atherosclerotic burden. • Plasma ceramides are independent predictors for a high atherosclerotic burden. • Our findings provide evidence supporting proatherogenic roles of ceramides. Abstract Background Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic links to atherosclerotic coronary artery disease (CAD) pathogenesis and are related to major adverse cardiovascular events (MACEs).
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Relationship between elevated plasma ceramides and plaque rupture in patients with ST-segment elevation myocardial infarction

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By Chinese Ministry, Jianjun Wu, Hui Dong, Weili Pan
| Atherosclerosis Verified
Highlights • This is the first study on plasma ceramides associated with plaque rupture (PR) evaluated by optical coherence tomography (OCT). • Elevated ceramide levels are independent predictors for PR in ST-segment elevation myocardial infarction (STEMI) patients. • Distinguishing PR from plaque erosion (PE) has important clinical implications. • Elevated ceramides may have a pathogenic link with occurrence of PR. Abstract Background and aims Ceramides (Cer) are an atherogenic substance.
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