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Weilin Pu

As seen in: Wiley Online Library, Annals of the Rheumatic Diseases, Frontiers
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Articles by Weilin Pu

Single‐cell RNA sequencing reveals the CRTAC1+ population actively contributes to the pathogenesis of spinal ligament degeneration by SPP1+ macrophage

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By Yulong Tang, Dachun Zhuo, Yuexin Yu, Weilin Pu
| Wiley Online Library Verified
cDC conventional dendritic cell CSI connection specificity index DEGs differentially expressed genes DSS degenerative spinal stenosis ECM extracellular matrix GO Gene Ontology GRN gene regulatory network Hh hedgehog HVGs highly variable genes IF immunofluorescence IHC immunohistochemistry JIA juvenile idiopathic arthritis L-R ligand-receptor PBS phosphate buffer saline PCs principal components PVDF polyvinylidene difluoride RSS regulon specificity score SCENIC Single-Cell Regulatory Network...
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A comprehensive cuproptosis score and associated gene signatures reveal prognostic and immunological features of idiopathic pulmonary fibrosis

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By Pulin Che, Weilin Pu, Yan Ren, Baicun Li
| Frontiers
Introduction Idiopathic pulmonary fibrosis (IPF) is a rare, chronic, progressive, fibrotic, interstitial lung disease with unknown etiology and pathogenesis (1). It mainly affects the middle-aged and elderly population with a poor prognosis. It is clinically characterized by progressive scarring or fibrosis of the interstitial lung, leading to a gradual decline in lung function and eventual death (2, 3).
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Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population

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By Jing Liu, Weilin Pu, Yuan Li, Yanyun Ma
| Annals of the Rheumatic Diseases Verified
Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population Jing Liu1,2, Weilin Pu1,2, Yuan Li1,2, Yanyun Ma2,3, Qi Zhu4, Wei Wan5, Chengde Yang6, Xiaofeng Wang1,2, Xingdong Chen1,7, Xiaodong Zhou8, John D Reveille8, Li Jin1,2, Hejian Zou9,10, Jiucun Wang1,11 1 State Key Laboratory of Genetic Engineering, Collaborative Innovation Center for Genetics and Development, School of Life Sciences, Fudan University, Shanghai, China 2 Human Phenome Institute, Fudan...
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Genetic association of non-MHC region with ankylosing spondylitis in a Chinese population

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By Jing Liu, Yuan Li, Weilin Pu, Yanyun Ma
| Annals of the Rheumatic Diseases Verified
Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the sacroiliac joints and spine.1 In order to examine overall genetic susceptibility of AS, several genome-wide association studies (GWASs) were performed in Caucasian populations, and a number of genetic polymorphisms in non-major histocompatibility complex (MHC) regions were found, such as ERAP1, IL23R as well as many others.2–6 However, only a small portion of the single nucleotide polymorphisms (SNPs) were...
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