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Articles by William Siegel
06.29.21 -- The Potential And Future Of Cell Therapy
Newsletter | June 29, 2021 By Armon Sharei, Ph.D., CEO, SQZ Biotechnologies While the field has made laudable progress in developing novel biomolecules that can be used to control cell function, little progress has been made on reliably delivering these materials to a cell. Here's a look at how to improve that. By Cell & Gene As the industry emphasizes its commitment to rare disease patients, gene therapy is an attainable opportunity to improve patients' lives.
Performance Challenging Fetal Bovine Serum (FBS) And FBS Alternatives
By William Siegel Growth performance testing in cell culture is an effective approach to making serum suitability and purchase decisions. An independent commercial testing lab conducted two separate and sequential growth promotion studies to underscore the need for pre-purchase lot performance testing with: (1) FBS, and (2) FBS alternatives.
02.23.21 -- 7 Steps Biotechs Should Do Before Partnering With A CRO
Application Note | By William Siegel, Avantor An independent commercial testing lab conducted two separate and sequential growth promotion studies to underscore the need for prepurchase lot performance testing with: (1) FBS, and (2) FBS alternatives. Article | Cytiva - Cell & Gene CAR-T therapies are expensive, and lentiviral vectors production represents a large portion of these costs. These practical tips guide efficient development of a lentivirus packaging cell line.
01.30.21 -- What You Need To Know Before Investing In A Bioprocessing Space
What You Need To Know Before Investing In A Bioprocessing Space By William Dow, Bioprocess Sales Engineer and Ma Sha, Ph.D., Head of Bioprocess Application Labs, Eppendorf Selecting the bioreactor that is best for your process and the dedicated space you have available requires consideration of many important factors. Is Your Definition Of Quality Culture The Same As The FDA's?
Performance Challenging Fetal Bovine Serum (FBS) And FBS Alternatives
By William Siegel Growth performance testing in cell culture is an effective approach to making serum suitability and purchase decisions. An independent commercial testing lab conducted two separate and sequential growth promotion studies to underscore the need for pre-purchase lot performance testing with: (1) FBS, and (2) FBS alternatives.
12.10.20 -- Cell Culture Media: Partners Poised To Meet Demand
Optimizing A Cell Culture Media Filtration Process Parker Bioscience Filtration A biopharmaceutical customer was reviewing its process for tryptone soya broth (TSB) and vegetable soya broth (VSB) production. The existing process incorporated five-step filtration, using three different media (glass fibre, cellulose and PVDF) at four different porosities.
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Breaking the Cycle of Arthritis Pain
by Bento Mascarenhas, MD, FACP, FACR, William Siegel, PT, DPT, Cert MDT, and Sudhir Vaidya, MD With more than 100 types of arthritis, affecting more than 46 million Americans, arthritis is a serious condition that does not have a one-size-fits-all solution. Treatments designed to be effective for specific types of arthritis are of strong importance among the millions of individuals affected by the condition, including those who still work.
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