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Wooseok Han

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Articles by Wooseok Han

ZET-Speech: Zero-shot adaptive Emotion-controllable Text-to-Speech Synthesis with Diffusion and Style-based Models

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By Sung Ju, Wooseok Han, Sung Ju Hwang, Eunho Yang
| arXiv
arXiv:2305.13831 (cs) Download a PDF of the paper titled ZET-Speech: Zero-shot adaptive Emotion-controllable Text-to-Speech Synthesis with Diffusion and Style-based Models, by Minki Kang and 3 other authors Download PDF Submission history From: Wooseok Han [ view email] [v1] Tue, 23 May 2023 08:52:00 UTC (648 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart...
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Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis

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By Wooseok Han, Xiaolei Ma, Carl J. Balibar, Bret Benton
| ACS Publications
The lipopolysaccharide biosynthesis pathway is considered an attractive drug target against the rising threat of multi-drug-resistant Gram-negative bacteria. Here, we report two novel small-molecule inhibitors (compounds 1 and 2) of the acyltransferase LpxA, the first enzyme in the lipopolysaccharide biosynthesis pathway. We show genetically that the antibacterial activities of the compounds against efflux-deficient Escherichia coli are mediated by LpxA inhibition.
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