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Articles by Xi Ma
CYB5R1 drives stemness and malignant progression via STAM2/STAT3 in chemotherapy-enriched triple-negative breast cancer
Abstract Triple-negative breast cancer (TNBC) frequently develops chemoresistance, but the mechanisms supporting tumor persistence remain incompletely understood. We integrated single-cell transcriptomic data with clinical cohort analyses to identify genes associated with chemotherapy exposure and prognosis. Malignant epithelial populations enriched after chemotherapy occupied terminal branches of the inferred pseudotime trajectory and exhibited higher stemness scores.
ABE-mediated dual targeting of TOX and ARHGEF1 synergistically enhances antitumor activity of tumor-infiltrating lymphocytes in PDAC
Abstract Tumor-infiltrating lymphocytes (TILs) represent a promising immunotherapeutic modality in solid tumors, yet their clinical efficacy in pancreatic ductal adenocarcinoma (PDAC) remains severely limited by inefficient expansion and functional exhaustion. TILs were isolated from pancreatic cancer surgical specimens and were found to exhibit progressive functional impairment under sustained tumor exposure.
Joint Identification of Groundwater Contamination Source and Heterogeneous Hydrogeological Parameters in LNAPL-Contaminated Sites Based on Deep Convolutional Encoder-Decoder Neural Networks
1 Introduction Hydrocarbon pollutants have low water solubility, exist as separate and immiscible phases after they spill into the subsurface (Newell et al., 1995), and are known as non-aqueous phase liquids (NAPLs). NAPLs with densities lower than that of water are known as light nonaqueous phase liquids (LNAPLs). Examples of LNAPLs include gasoline, diesel, and motor oils (Zhang, 2007).
Enzyme-responsive peptide dendron nanoassemblies for targeting and eliminating intracellular drug-resistant bacteria
Abstract Certain intracellular pathogens can reside within cells to evade host immune defenses and exhibit high tolerance to antibiotics. Current treatments for intracellular bacterial infections are limited by poor cellular penetration, inadequate targeting of infected sites, and inefficacy against drug-resistant bacteria.
Bilirubin directly activates RIPK3 to induce non-classical necroptosis
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Abstract Bilirubin, a byproduct of heme metabolism, is traditionally recognized for its antioxidant properties. However, its accumulation under pathological conditions can result in severe clinical manifestations, including neurotoxicity. Here, we report that bilirubin acts as an activator of receptor-interacting protein kinase 3 (RIPK3), inducing necroptosis and contributing to neurotoxic effects.
By Qian Xue, Xi Ma, Ziyuan Chen, Jiawen Wu, Wenhao Bao, Li Zhou Verified, Wei Yi, Min Wu, Wenwen Xu, Rongrong He, Jingcheng Feng, Yameng Hu, Xi Chen, Daolin Tang, Xin McRae Chen, Jinbao Liu, Feifei Ge, Siyan Liao, Xintian Wu
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Nature
Verified
Comparison and Interpretability Analysis of Deep Learning Models for Classifying the Manufacturing Process of Pigments Used in Cultural Heritage Conservation
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Commentary on ‘Model of Predicting Fear of Cancer Recurrence in Patients With Digestive Tract Cancer: A Cross‐Sectional Study’
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Geochemical Indicators on the Central Tibetan Plateau Lake Sediments: Historical Climate Change and Regional Sustainability
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Insects | Free Full-Text | Extrinsic and Intrinsic Competition between Chouioa cunea Yang and Tetrastichus septentrionalis (Hymenoptera: Eulophidae), Two Pupal Parasitoids of the Fall Webworm, Hyphantria cunea (Lepidoptera: Erebidae)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
A reduced smoothed integration scheme of the cell‐based smoothed finite element method for solving fluid-structure interaction on severely distorted meshes - He - International Journal for Numerical Methods in Fluids - Wiley Online Library
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. REFERENCES 1, , . Computational Fluid–Structure Interaction: Methods and Applications. John Wiley & Sons; 2013. 2, , . Numerical methods for fluid–structure interaction—a review. Commun Comput Phys. 2012; 12(2): 337-377. 3, . An overview of the combined interface boundary condition method for fluid–structure interaction. Arch Comput Methods Eng. 2017; 24(4): 891-934. 4.
Highly Flexible and Self‐Standing Covalent Organic Framework-Metal-Organic Framework (COF-MOF) Composite Crystalline Porous Material (CPM) Membrane for Molecular Separation - Ma - Advanced Functional Materials - Wiley Online Library
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202312203-sup-0001-SuppMat.pdf2 MB Supporting Information References 1, , Science 2011, 333, 712. 2, , Nature 2012, 488, 313. 3a) , , , J. Am. Chem. Soc. 2019, 141, 1807; b) , , , , , , , Nat. Rev. Chem. 2022, 6, 881; c) , , Chem. Soc. Rev. 2020, 49, 8469; d) , , , , , , Chem. Soc. Rev. 2022, 51, 8300; e) , , , , , , , , , , , Small 2022, 18, 2202928; f) , , , , , Nano Res.
Highly Flexible and Self‐Standing Covalent Organic Framework-Metal-Organic Framework (COF-MOF) Composite Crystalline Porous Material (CPM) Membrane for Molecular Separation - Ma - Advanced Functional Materials - Wiley Online Library
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202312203-sup-0001-SuppMat.pdf2 MB Supporting Information References 1, , Science 2011, 333, 712. 2, , Nature 2012, 488, 313. 3a) , , , J. Am. Chem. Soc. 2019, 141, 1807; b) , , , , , , , Nat. Rev. Chem. 2022, 6, 881; c) , , Chem. Soc. Rev. 2020, 49, 8469; d) , , , , , , Chem. Soc. Rev. 2022, 51, 8300; e) , , , , , , , , , , , Small 2022, 18, 2202928; f) , , , , , Nano Res.
MGP‐1 Plagioclase: A Potential Element and Sr Isotope Reference Material for In Situ Microanalysis
Plagioclase, one of the most common rock-forming minerals, can provide useful information on the crystallisation environment, magmatic evolution and thermal history of host rocks. Owing to matrix effects, trace element and Sr isotope in situ measurements in plagioclase have been hindered by a shortage of reference materials for quality control and method validation.
Research on SLAM and Path Planning Method of Inspection Robot in Complex Scenarios
Abstract : Factory safety inspections are crucial for maintaining a secure production environment. Currently, inspections are predominantly performed manually on a regular basis, leading to low efficiency and a high workload. Utilizing inspection robots can significantly improve the reliability and efficiency of these tasks. The development of robot localization and path planning technologies ensures that factory inspection robots can autonomously complete their missions in complex environments.
Smart Agriculture and Rural Revitalization and Development Based on the Internet of Things under the Background of Big Data
Abstract : Smart agriculture refers to the specific performance of the smart economy in the field of agriculture; it is a form of agricultural smart economy and an important part of the smart economy. It has played a certain role in promoting rural revitalization and development. The purpose of this paper was to study the role of smart agriculture based on the Internet of Things in rural revitalization and development under the background of big data.
Sodium caprylate improves intestinal mucosal barrier function and antioxidant capacity by altering gut microbial metabolism
Sodium caprylate improves intestinal mucosal barrier function and antioxidant capacity by altering gut microbial metabolism† Short-chain fatty acids (SCFA) produced by gut microbial metabolism have been reported to regulate the immunological response and intestinal health of the host by activating G protein-coupled receptors (GPR). It is unclear whether medium-chain fatty acids (MCFA) improve the intestinal barrier function by activating GPR.
A case study targeting K fertilizer chemical synthesis with complete valorization of extraction by-products options
A case study targeting K fertilizer chemical synthesis with complete valorization of extraction by-products options Here, we demonstrate the processing techniques for KNO3 preparation through green chemical reaction engineering of abundant rock-forming minerals to achieve materials sustainability.
Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets
Background: The vast majority of substances used as alternatives to antibiotics produce inconsistent results and rarely equal the effectiveness of in-feed antibiotics. Objective: This study evaluated the effects of the combined use of sodium butyrate (SB) and reduced antibiotics in a piglet diet in promoting performance and to control weaning diarrhea.
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