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Articles by Xia Mao
Endoplasmic reticulum stress promotes leukemic plasmacytoid dendritic cell differentiation skewing and immune suppression in acute myeloid leukemia
Abstract Mature plasmacytoid dendritic cell proliferation associated with acute myeloid leukemia (pDC-AML) is a distinct entity with poor prognosis. Yet, the mechanisms underlying the immune evasion and aberrant pDC expansion remain poorly understood. We performed multi-omic profiling of 18 pDC-AML cases, along with 207 non-pDC-AML and 16 BPDCN cases as controls.
Adult Erythroblastic Sarcoma With PCM1::JAK2 Fusion and a Novel NOP10::NUTM1 Fusion Complicated by Secondary HLH
1 Introduction Erythroblastic sarcoma (ES) is an exceedingly rare, mass-forming proliferation of immature erythroid cells that may occur with or without overt acute erythroid leukaemia (AEL) [1]. Because the number of reported cases remains limited, its diagnostic criteria, immunophenotypic spectrum, and molecular landscape remain incompletely defined [2].
Long-term follow-up demonstrates the curative potential of dual CD19/CD22 CAR-T-cell therapy alone or combined with autologous stem cell transplantation in TP53-altered relapsed/refractory B-cell non-Hodgkin lymphoma | Signal Transduction and Targeted The
Abstract The prognostic implications of TP53 alterations in patients with relapsed or refractory (r/r) aggressive B-cell non-Hodgkin lymphoma (B-NHL) treated with chimeric antigen receptor (CAR) T-cell therapy remain inadequately characterized, particularly with respect to long-term outcomes.
Efficacy and safety of autologous CD5-KO anti-CD5 CAR-T cells in relapsed/refractory CD5+ hematological malignancies
Keywords anti-CD5 CAR-T cell CD5 knockout CD5 positive hematological malignancies adverse events hCD5 knockin murine models Introduction CD5, a cysteine-rich scavenger receptor, plays a multifaceted role in modulating immune responses.
C-COMPASS: A Neural Network Tool for Multi-Omic Classification of Cell Compartments
Abstract Functional compartmentalization in eukaryotic cells is essential for maintaining physiological processes. The development of systematic organelle proteomics techniques, such as Protein Correlation Profiling (PCP) and Localization of Organelle Proteins by Isotope Tagging (LOPIT), has enhanced our understanding of organelle dynamics and protein localization. However, the complexity of the data and the need for advanced computational skills limit their accessibility.
Inhibition of PbeXTH1 and PbeSEOB1 is required for the Valsa canker resistance contributed by Wall‐associated kinase gene MbWAK1
CONFLICT OF INTEREST STATEMENT The author declares no competing interests. Supporting Information Filename Description ppl14330-sup-0001-Supinfo.pdfPDF document, 1.2 MB Table S1: PCR primer sequences used for vector construction Table S2: List of primer sequences used for qRT-PCR analysis. Table S3: Prediction of cis-elements in the promoter region of MbWAK1. Figure S1: Protein sequences alignment with MABA1460 and A. thaliana WAKs (WAK1, AT1G21250; WAK3, AT1G21240; and WAK5, AT1G21230).
Antigen-specific immune responses to influenza vaccine in utero
J Clin Invest. 2007 Jun 1; 117(6): 1637–1646. Deepa Rastogi,1 Chaodong Wang,2 Xia Mao,3 Cynthia Lendor,3 Paul B. Rothman,4 and Rachel L. Miller3 Deepa Rastogi 1Children’s Hospital at Montefiore, Albert Einstein College of Medicine, New York, New York, USA. 2Department of Neurology, Jiangxi Provincial People’s Hospital, Nanchang, People’s Republic of China.
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