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Abstract CD8+ T cell immune responses are critical for combating infectious diseases and tumours1,2,3. Antigen cross-presentation, primarily occurring at the endoplasmic reticulum (ER) of dendritic cells, is essential for protein-based vaccines to induce CD8+ T cell responses4. Current efforts have focused on antigen delivery at the tissue and cellular levels, whereas subcellular delivery has been limited to facilitating antigen escape from lysosomes into the cytosol.
X. Wang, T. Guo, J. Chen, X. Li, Y. Zhou and Z. Pan, Chem. Commun., 2018, 54, 4661 DOI: 10.1039/C7CC08888D If you are not the author of this article and you wish to reproduce material from it in a third party non-RSC publication you must formally request permission using RightsLink. Go to our Instructions for using RightsLink page for details.
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