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Highlights: • The frequency of genetic mutations is high in pure-solid stage I lung cancer. • Genetic mutations are related to adverse survival in radiological pure-solid tumors. • Lymph node invasion is a valuable factor related to prognosis. Abstract Purpose To investigate whether genetic status is associated with the prognosis of patients with clinical stage (c-stage) I non-small cell lung cancer (NSCLC) with radiological pure-solid manifestations.
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