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Abstract Permafrost carbon vulnerability, particularly concerning temperature thresholds and old carbon mobilization, remains a critical uncertainty in climate projections. Through a five-year, multi-level warming experiment on the Tibetan Plateau, we investigate these dynamics using >40,000 hourly flux measurements combined with vertical CO2 concentration and δ13C-CO2 profiling.
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data sets supporting the findings of this study are openly available from the following sources. Temperature and precipitation data were obtained from the Third Pole Meteorological Forcing Dataset (TPMFD) (https://doi.org/10.11888/Atmos.tpdc.300398) and the China Meteorological Forcing Dataset (CMFD) (https://data.tpdc.ac.cn).
1. Introduction Prostate cancer (PCa) accounts for an estimated 29% of all new incident cases and has become the second leading cause of cancer-related deaths (11%), according to the American Cancer Society (ACS) [1].
4.1. Immunohistochemistry 4.1.1. Glypican-3 (GPC3) GPC3 is a carcinoembryonic antigen, a member of the phosphatidylinositol proteoglycan family of membrane-bound acetylated heparan sulfate proteoglycans, expressed in fetal liver and progenitor cells as well as in many HCC cases and other tissues [33]. According to a study by Coral et al., GPC3 has a sensitivity of approximately 65% and a specificity of 96% for diagnosing HCC [3].
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