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Abstract Skin cutaneous melanoma (SKCM) is an aggressive malignancy with variable prognosis and response to immunotherapy. Regulatory T cells (Tregs) play a crucial role in immune suppression within the tumor microenvironment. However, the clinical significance of Treg-related genes in SKCM remains unclear. We constructed a Treg-related gene signature for SKCM using bulk RNA-seq data from TCGA and three GEO cohorts.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.