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Articles by Xinyu Deng
Empagliflozin attenuates AGE-BSA/high-glucose-induced inflammation in C2C12 myotubes associated with suppression of the RAGE/NF-κB pathway
Abstract Introduction: Empagliflozin is an established sodium-glucose cotransporter 2 inhibitor with reported anti-inflammatory activity, but its effects on advanced glycation end product/high-glucose-induced inflammatory injury in skeletal muscle cells remain unclear.
Metabolomics-assisted evaluation of differences and clinical value between ablation and surgical treatment for lung adenocarcinoma
Abstract The optimal transition from surgery to minimally invasive ablation for early lung adenocarcinoma requires elucidation of their differential metabolic impacts and clinical benefits. Using MALDI-MS platform, this study investigated 40 patients (15 ablation, 25 surgery) to characterize treatment-specific metabolic signatures and evaluate diagnostic performance.
Surface Solvent Cleaning-Assisted Vapor-Phase Passivation Strategies for High-Quality Perovskite Thin Films Grown by Vapor–Solid Reaction Click to copy article link Article link copied!
Cite Jump to ExpandCollapse Energy, Environmental, and Catalysis ApplicationsMarch 17, 2026 Surface Solvent Cleaning-Assisted Vapor-Phase Passivation Strategies for High-Quality Perovskite Thin Films Grown by Vapor–Solid Reaction Click to copy article linkArticle link copied! Mengjun Liu Mengjun Liu State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, China Shenghan Hu Shenghan Hu State Key Laboratory of Advanced...
Noncanonical function of sphingosine kinase 2 (SPHK2) sustains hepatic triglyceride homeostasis
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest. DATA AVAILABILITY STATEMENT In silico data analysis was performed using custom R Scripts (R Version 3.5.3) designed especially for this research. R scripts are available on GitHub (https://github.com/love1camille/Sphk2scRNAseq/). The previously published data sets re-analysed in this study were obtained from Gene Expression Omnibus (GEO), through the accession code (GSE182365 and GSE166504).
Stoichiometric Gradient Rebalancing Achieves Surface Reconstruction and Bulk Homogenization in High-Performance Vapor-deposited Perovskite Solar Cells†
Stoichiometric Gradient Rebalancing Achieves Surface Reconstruction and Bulk Homogenization in High-Performance Vapor-deposited Perovskite Solar Cells† Vapor-deposited perovskites offer excellent reproducibility and scalability, making them highly promising for commercialization. However, limited understanding of the compositional and structural characteristics of their films hinders further improvements in crystal quality and device performance.
DNA Methylation–Mediated Downregulation of SDK1 Promotes COPD Progre | COPD
Introduction Chronic obstructive pulmonary disease (COPD), a progressive respiratory disorder characterized by persistent airflow limitation and chronic inflammation, imposes a substantial global health and economic burden owing to its escalating morbidity and mortality.1–3 Although environmental risk factors, including cigarette smoking and air pollution, are well documented, the genetic and epigenetic mechanisms driving COPD heterogeneity remain incompletely understood.4–6 Although...
Dynamics of CH/n Hydrogen Bond Network Probed by Time-Resolved CARS Spectroscopy
Dynamics of CH/n Hydrogen Bond Network Probed by Time-Resolved CARS Spectroscopy Hydrogen bond (HB) networks are essential for stabilizing molecular structures in solution and govern the solubility and functionality of molecules in aqueous environment. HBs are important in biological processes such as enzyme-substrate interactions, protein folding, and DNA replication. However, the exact role of weakly-polarized C-H bond as HB proton donors in solution, such as CH/n HB, remains mostly unknown.
Staged or simultaneous operations for ventriculoperitoneal shunt and cranioplasty: Evidence from a meta‐analysis
Statistical analysis Data synthesis and analysis was used Review Manager (version 5.3, Cochrane Collaboration). The odds ratios (ORs) with 95% confidence intervals (CIs) was applied as the effect indicator for the dichotomous variables. We calculated 95% CIs performing the Mantel–Haenszel statistical method. I-square (I2) statistics and Q tests were applied to evaluate the impact of study heterogeneity on the findings of this meta-analysis.
Paeoniflorin Protects against Acetaminophen-Induced Liver Injury in Mice via JNK Signaling Pathway
Open AccessArticle by Xinyu Deng 1, Yubing Li 1, Xing Li 2, Zhenpeng Zhang 1, Shu Dai 1, Hefei Wu 1, Fangling Zhang 1, Qichao Hu 1, Yuan Chen 1, Jinhao Zeng 3,* and Xiao Ma 1,* 1 State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China 2 Department of Pharmacy, Chinese PLA General Hospital, Beijing 100039, China 3 Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610072,...
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