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Abstract Background: Kawasaki disease (KD) is an acute systemic vasculitis in children, but the characteristics of the B-cell receptor (BCR) repertoire during acute disease and their association with coronary artery lesions (CALs) remain poorly understood. Methods: High-throughput sequencing of BCR heavy-chain (BCR-H) CDR3 regions was performed in 22 children, including 9 healthy controls and 13 patients with KD, of whom 9 had no CAL and 4 had CAL.
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