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Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The LC-MS/MS raw data and search parameters have been deposited to the Proteomics Identifications Database (PRIDE) under the dataset identifier PXD079676. Processed data (peptide lists, protein lists, LFQ intensities, and statistical metrics) are provided in Tables .
1 Introduction The precise subcellular localization of proteins is crucial for the proper functioning of eukaryotic cells, and deviations from the normal localization are closely linked to a variety of diseases [1], including genetic disorders [2, 3]. Nuclear lamina, a fibrous layer beneath the inner nuclear membrane that connects to endoplasmic reticulum (ER), is essential for cell survival [4].
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