Abstract The great complexity of the human connectome motivates the study of a simpler neural network. For that purpose, the Ising Model was applied on experimental data on the synaptic connectivity of Caenorhabditis elegans (C. elegans) in resting-state, assigning a binary variable (representing active or inactive states) to each neuron in the network. The dynamics of this system is postulated as a message passing network, encoded by the Belief Propagation algorithm (BP) in its criticality region.