CONFLICT OF INTEREST STATEMNET The authors declare no conflicts of interest. Supporting Information REFERENCES , , , , & (2015). GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers. Softwarex, 1–2, 19–25. , , , & (2021). Ultrasound-assisted extraction of phenolic acids, flavonols, and flavan-3-ols from muscadine grape skins and seeds using natural deep eutectic solvents and predictive modelling by artificial neural networking.