Abstract Mineralization and vascularization are essential processes for implant osseointegration around titanium, and insufficient surface bioactivity affects its clinical performance; thus, surface modification of implants is necessary. This study aimed to establish a sodium alginate/collagen/troxerutin coating on the surface of titanium to promote angiogenic and osteogenic ability. The results indicate that the material has satisfactory biocompatibility in terms of cell viability.
