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Ya’nan Zhen

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Articles by Ya’nan Zhen

Identification of the SNHG14/hsa-miR-577/CLIC4 ceRNA axis reveals the association of CLIC4 with stromal activation and microenvironment remodeling in colorectal cancer

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By Ruixue Xiao, Runze Jiang, Xing Chen, Cunbao Chen, Ya’nan Zhen
| Nature Verified
Abstract Colorectal cancer (CRC) is a prevalent malignancy with complex molecular regulatory mechanisms. In this study, we analyzed transcriptomic profiles from The Cancer Genome Atlas (TCGA) and identified differentially expressed mRNAs, miRNAs, and lncRNAs. Using integrative bioinformatics approaches, we constructed a CRC-specific ceRNA regulatory network to screen candidate regulatory molecules involved in CRC progression.
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