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Abstract Research question Does the aggregation of M2 macrophages affect the expression of GRIM-19 in adenomyosis༟ Design Except the collecting of endometrial tissues, GRIM-19 small interfering RNA were constructed to regulate the expression of GRIM-19 in Human endometrial stromal cells (hESCs). At the same time, hESC cells were co-cultured with M2 macrophages to detect the influence of M2 macrophages in hESC cells.
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