1 Introduction Plants provide an abundant, renewable, and sustainable resource of bioactive molecules. Among natural sources, toxic peptides from plants such as defensins, thionins (α/β, γ), knottin-like peptides, lipid transfer proteins, and hevein-like peptides evolved differently from animal- or microbial-origin peptides, and other antimicrobial peptides (AMPs) due to the presence of cysteine residues, forming numerous disulfide bridges that stabilized their backbone [1-5].