Introduction Growth hormone (GH) therapy was originally developed for medical indications such as growth hormone deficiency (GHD) or specific genetic and systemic disorders associated with growth failure.1 The indications approved by the US FDA include GHD, small for gestational age (SGA) without catch-up growth, chronic renal insufficiency, Turner syndrome, SHOX gene haploinsufficiency, Prader-Willi syndrome, idiopathic short stature (ISS), and Noonan syndrome.2 In Korea, while the National...