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Abstract Delayed postoperative hyponatremia after transsphenoidal pituitary surgery has a reported incidence of 5–30%, yet how much of this variability reflects biology rather than differences in postoperative sodium surveillance has not been quantified within a single cohort. We retrospectively studied 285 consecutive adults who underwent microscopic transsphenoidal surgery for pituitary adenoma by a single team between 2004 and 2025.
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