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Abstract Objective: This study sought to create a CT-based clinical deep learning radiomics (CDLR) model to noninvasively differentiate between pyelocaliceal upper tract urothelial carcinoma (UTUC) and xanthogranulomatous pyelonephritis (XGP) preoperatively, aiding in personalized treatment decisions. Methods: A retrospective analysis included 161 patients with pathologically confirmed pyelocaliceal UTUC or XGP following surgery.
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