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Yong D. Park

Augusta
As seen in: Wiley Online Library, BioRxiv
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Articles by Yong D. Park

Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer

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By Susmita Ghosh Verified, Fan Fan, Reid T. Powell, Yong D. Park
| BioRxiv
Abstract Background: KRAS is frequently mutated in the tumors of patients with metastatic colorectal cancer (mCRC) and thus represents a valid target for therapy. However, the strategies of targeting KRAS directly and targeting the downstream effector mitogen-activated protein kinase kinase (MEK) via monotherapies have shown limited efficacy. Thus, there is a strong need for novel, effective combination therapies to improve MEK-inhibitor efficacy in patients with KRAS-mutated mCRC.
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Divine presence in Human world: The place of the Communicatio Idiomatum in Lundensian theology

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By Yong D. Park
| Wiley Online Library Verified
REFERENCES (1966). The theology of Martin Luther. Fortress Press. (2010). Cross narratives: Martin Luther's Christology and the location of redemption. Princeton Theological Monograph Series 135. Pickwick Publications. (1951). Christus Victor: An historical study of the three main types of the idea of atonement. Translated by A. G. Hebert. American ed. Macmillan. (1958). Eucharist and sacrifice. Muhlenberg Press. (1982). Luther, witness to Jesus Christ: Stages and themes of the reformer's Christology.
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Sample multiplexing for retinal single-cell RNA-sequencing

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By Justin Ma, Ting Chu, María Prieto, Yong D. Park
| BioRxiv
Abstract Single-cell RNA sequencing (scRNA-seq) is a powerful tool for evaluating cell-type specific transcription but can be challenging to apply to rare cell populations. Efficient collection of low abundance cell types can be achieved by pooling biological samples, but this precludes resolution of sample origin together with phenotypic data.
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Long-term efficacy and safety of cannabidiol (CBD) in children with treatment-resistant epilepsy: Results from a state-based expanded access program

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By Jamie Pope, Yong D. Park, Daniel F. Linder, J. Robert Flamini
| epilepsybehavior.com
Highlights • Children with treatment-resistant epilepsy received increasing doses of cannabidiol. • Incidence of all and major seizures was significantly reduced over 36 months. • Mean increase in seizure-free days was > 5 in each 28-day treatment period. • Cannabidiol was generally well tolerated in doses up to 50 mg/kg/day. Abstract Introduction An intermediate-sized, multicenter, expanded-access study was opened in 2015 through the support of the State of Georgia.
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