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Abstract UL16-binding protein 2 (ULBP2) is a stress-inducible NKG2D ligand whose expression has been linked to both tumor recognition and poor clinical outcomes. These observations are difficult to interpret from expression measurements alone. We review evidence on ULBP2 regulation, immune function, and therapeutic targeting, distinguishing surface ligand from intracellular and soluble protein.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
