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Abstract Primary adenoid cystic carcinoma of the breast (ACCB) is a rare salivary gland–type malignancy characterized by biphasic luminal epithelial and myoepithelial/basal differentiation. Although most ACCBs exhibit a triple-negative phenotype, hormone receptor–positive tumors occur, and evidence guiding endocrine therapy is limited. A 42-year-old woman presented with a gradually enlarging right breast mass.
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