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Abstract Diabetic sarcopenic obesity (SO) is a complex metabolic condition characterized by the coexistence of obesity, diabetes, and sarcopenia, leading to poor prognosis. Astragalus, is a key herb in spleen-strengthening formulas, but its pharmacological mechanisms against diabetic SO remain unclear. Drug- and disease-related genes for Astragalus, obesity, diabetes, and sarcopenia were retrieved from public databases.
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