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Articles by Yusuke Kimura
Heated tobacco product aerosol exposure induces lung inflammation associated with altered miR-96-5p and FoxO3a expression in mice
Abstract Heated tobacco products (HTPs) have recently become increasingly popular among smokers, mainly in Europe and the Western Pacific region, based on the argument that they are healthier alternatives to conventional cigarettes. However, scientific evidence in support of this argument is insufficient. The aim of the present study was to determine the effects of exposure to HTPs aerosol on the lungs of mice.
Gravitational and mechanical forces shape mitochondrial translation
Abstract Life on Earth has evolved in a form suitable for the gravitational force. Although the pivotal role of gravity in gene expression has been suggested, the molecular details remain unclear. Here, we show that mitochondria utilize gravity to activate protein synthesis within the organelle. Genome-wide ribosome profiling reveals reduced mitochondrial translation in mammalian cells and Caenorhabditis elegans under microgravity.
Group 8 metallocenes as single-source precursors for the synthesis of light-element-stabilized FCC phases under extreme conditions
ABSTRACT Metallocenes are promising single-source precursors for the synthesis of transition-metal carbides and hydrides due to their atomic-scale mixing of metal, carbon, and hydrogen. In this study, we investigated the high-pressure and high-temperature (HP–HT) behavior of group 8 metallocenes, ferrocene [Fe(C5H5)2] and ruthenocene [Ru(C5H5)2], at pressures up to 68 GPa using a laser-heated diamond anvil cell.
A Case of Laparoscopic Distal Gastrectomy for Early Gastric Cancer Associated With an Upside-Down Stomach: Sac-First Dissection Before Lymphadenectomy
Disclosure We, the undersigned, agree to the following: All authors listed have contributed significantly to the study, and all are in agreement with the content of the manuscript. No part of this work has been published or is under consideration for publication elsewhere. Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data supporting this case report are included within the article.
Outcomes in Health‐Related Quality of Life and Impact of Urinary Incontinence on Health‐Related Quality of Life 7 Years After Robot‐Assisted Radical Prostatectomy - Kimura - International Journal of Urology - Wiley Online Library
Objective We evaluated the long-term outcomes in health-related quality of life (QOL) after robot-assisted radical prostatectomy (RARP) and the factors influencing them. Methods Overall, 246 patients who underwent RARP were included. The Expanded Prostate Cancer Index Composite (EPIC) and Short Form-8 (SF-8) questionnaires were utilized. Continence was defined as a score of ≤ 1 on question 1 of the International Consultation on Incontinence Questionnaire-Short Form.
Clinical significance of intraoperative bidirectional corticocortical evoked potential monitoring to evaluate language function
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Development of Low‐Viscosity Silicone Rubber With Variable Hardness for Precise Microfabrication
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description pat70089-sup-0001-FigureS1.tifTIFF image, 540.3 KB Figure S1. Stress–strain curves of LVS and Sylgard 184 before and after 1 MeV EB irradiation. pat70089-sup-0002-FigureS2.tifTIFF image, 502.3 KB Figure S2. Transmittance of Sylgard 184 and LVS sheets as a function of absorbed dose of 1 MeV EB. pat70089-sup-0003-FigureS3.tifTIFF image, 388.5 KB Figure S3.
BLOC: buildable and linkable organ on a chip
Abstract Microphysiological systems (MPSs) are attractive alternatives to animal experiments in physiology, pathophysiology, and drug development. However, conventional MPSs are designed for specific applications and have low versatility and scalability. Here, we developed a ″Buildable and Linkable Organ on a Chip″ (BLOC) to construct diverse MPSs. The Culture, Control, and Analysis BLOCs were standardized to the same size and linked using inlet/outlet joints for perfusion.
[2409.02819] Efficient Simulation of 1D Long-Range Interacting Systems at Any Temperature
[Submitted on 4 Sep 2024] Title:Efficient Simulation of 1D Long-Range Interacting Systems at Any Temperature View a PDF of the paper titled Efficient Simulation of 1D Long-Range Interacting Systems at Any Temperature, by Rakesh Achutha and 3 other authors View PDF HTML (experimental) Abstract:We introduce a method that ensures efficient computation of one-dimensional quantum systems with long-range interactions across all temperatures.
Development of irreversible pancreatic ductal change triggered by pancreatic duct stenting in chronic pancreatitis
Background and Aim Stent-induced ductal change is a complication of endoscopic pancreatic stent placement for chronic pancreatitis, potentially leading to irreversible changes that may contribute to pancreatic dysfunction. This study aimed to examine the long-term outcomes of stent-induced ductal change and evaluate factors that correlate with the development of irreversible ductal changes.
An anatomo-functional study of the interactivity between the paracentral lobule and the primary motor cortex
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Gravitational and mechanical forces drive mitochondrial translation
Abstract Life on Earth has evolved in a form suitable for the gravitational force of 1 × g. Although the pivotal role of gravity in gene expression has been revealed by multi-omics approaches in space-flown samples and astronauts, the molecular details of how mammalian cells harness gravity have remained unclear. Here, we showed that mitochondria utilize gravity to activate protein synthesis within the organelle.
Toxicological Sciences
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Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion-FAK axis
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Convergence condition of simulated quantum annealing for closed and open systems
Abstract Simulated quantum annealing is a generic classical protocol to simulate some aspects of quantum annealing and is sometimes regarded as a classical alternative to quantum annealing in finding the ground state of a classical Ising model. We derive a generic condition for simulated quantum annealing to converge to thermal equilibrium at a given, typically low, temperature. Both closed and open systems are treated.
Correction: The circadian rhythm of bladder clock genes in the spontaneously hypersensitive rat
The word “hypertensive” is misspelled in the article title. The correct title is: The circadian rhythm of bladder clock genes in the spontaneously hypertensive rat. The correct citation is: Kimura Y, Honda M, Sasaki R, Yumioka T, Iwamoto H, Tsounapi P, et al. (2019) The circadian rhythm of bladder clock genes in the spontaneously hypertensive rat. PLoS ONE 14(7): e0220381. https://doi.org/10.1371/journal.pone.0220381 Citation: Kimura Y, Honda M, Sasaki R, Yumioka T, Iwamoto H, Tsounapi P, et al.
The circadian rhythm of bladder clock genes in the spontaneously hypersensitive rat
Loading metrics Open Access Peer-reviewed Research Article Yusuke Kimura , Masashi Honda, Ryo Sasaki, Tetsuya Yumioka, Hideto Iwamoto, Panagiota Tsounapi, Shuichi Morizane, Katsuya Hikita, Mitsuhiko Osaki, Futoshi Okada, Atsushi Takenaka Yusuke Kimura, Masashi Honda, Ryo Sasaki, Tetsuya Yumioka, Hideto Iwamoto, Panagiota Tsounapi, Shuichi Morizane, Katsuya Hikita, Mitsuhiko Osaki, Futoshi Okada Published: July 25, 2019 https://doi.org/10.1371/journal.pone.0220381 Figures Abstract Circadian...
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