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Zan Hou

As seen in: Wiley Online Library, Frontiers in Immunology
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Articles by Zan Hou

Upfront surgery versus neoadjuvant chemoimmunotherapy versus neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma in elderly patients: a multicenter cohort study

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By Zan Hou, Yixiang Zhu, Mei Lan, Xueyu Chen, Lei Xu, Yuqin Cao, Lijun Liang, Yongkui Yu, Xuefeng Leng, Linrui Gao, Jian Zheng, Lei Wu, Zefen Xiao, Wei Huang, Ming Wu, Wencheng Zhang, Lin Peng, Yiting Sun, Qifeng Wang
| Frontiers in Immunology
Abstract Purpose: The optimal treatment strategy for elderly patients (aged ≥65 years) with operable locally advanced esophageal squamous cell carcinoma (ESCC) remains controversial. This study aimed to compare the survival outcomes of upfront surgery (US), neoadjuvant chemoimmunotherapy (nCIT), and neoadjuvant chemoradiotherapy (nCRT) in this population.
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Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

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By Yixiang Zhu, Mei Lan, Danming He, Zan Hou
| Wiley Online Library Verified
1 Introduction The brain is one of the most common sites for metastasis from lung cancer, and patients with brain metastases (BM) have a poorer prognosis than those without BM[1] Lung cancer is pathologically classified into: non-small cell lung cancer (NSCLC), accounting for 80–85% of cases, and small cell lung cancer (SCLC), accounting for 15–20% of cases.[2] Among patients with non-metastatic NSCLC, the risk of developing BM is 11% for lung adenocarcinoma, 6% for squamous cell carcinoma...
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