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1 Introduction Ketamine has expeditious and robust antidepressant effects, triggering significant theoretical and clinical progress in the treatment of major depressive disorder (MDD) [1]. Ketamine has been used as a rapid-acting antidepressant for depression patients, while simultaneously diminishing the intensity of suicidal ideation [2-5]. Previous studies have shown that the antidepressant and anti-suicidal effects of six repeated ketamine injections can persist for more than two weeks [6, 7].
1 INTRODUCTION There are five generally recognized tastes: sour, sweet, bitter, salty, and umami (Zhang et al., 2021). Humans generally prefer sweetness, umami, and saltiness, as these tastes elicit pleasant sensations, whereas bitterness is perceived as unpleasant. The umami taste was recognized relatively recently; it was initially proposed in the early 20th century and only acknowledged as a fundamental taste in 1985 (Kawamura & Kare, 1987).
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