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Acute otitis media (AOM) is one of the most common infections of childhood. Recurrent AOM affects a subset of children, causing substantial socioeconomic implications. Multivalent pneumococcal conjugate vaccine (PCV) introduction has resulted in alteration in the incidence and predominant otopathogens of AOM. Our current evidence base for the use of antimicrobial chemoprophylaxis in recurrent AOM is based on limited pre-PCV data from over two decades ago.
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