Confined PtNi catalysts for enhanced catalytic performances in one-pot cellobiose conversion to hexitols: a combined experimental and DFT study Ni nano-clusters were confined inside the alumina matrix through Ni-Al layered double hydroxides (NiAl-LDHs) decomposition methods and studied in one-pot cellobiose conversion to hexitols. TEM results indicated that very tiny Ni particles at mean particle size 0.95 nm were successfully achieved in Al2O3 matrix on 5%NiAl-MMO catalysts.