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Mycophenolate mofetil (MMF) is frequently used in treatment of systemic autoimmune diseases including systemic lupus erythematosus (SLE). It reversibly inhibits inosine monophosphate dehydrogenase, thus reducing the downstream production of guanosine in the de novo synthesis pathway, and this, in turn, selectively inhibits lymphocyte proliferation and its activity [1].
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