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Abstract Trace metal ions act as essential cofactors but exhibit concentration-dependent cytotoxicity that shapes Chinese hamster ovary (CHO) cell culture performance. This work systematically evaluated six transition metal ions (Fe3+, Mn2+, Cu2+, Zn2+, Co2+, Ni2+) and their metal oxide nanoparticles for their impacts on cell proliferation, metabolism and protein N-glycosylation.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
