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Abstract Accurate spindle formation is vital for mitotic progression and genomic DNA segregation, with γ-tubulin ring complex (γ-TuRC) mediating microtubule nucleation, and NEDD1 serving as its essential recruitment/anchoring adaptor. However, the mechanisms underlying the regulation of NEDD1 remain largely elusive. Here, we identify a pathway that controls NEDD1 stability during mitosis.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
