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Abstract Parkinson's disease (PD) is a common neurodegenerative disorder with a complex pathogenesis linked to ferroptosis, apoptosis, inflammation, and oxidative stress. Mounting evidence has demonstrated that the protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway is deeply involved in PD pathogenesis and acts as a key regulator of ferroptosis.
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