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Keywords ongoing symptomatic Covid Post-Covid Syndrome SARS-CoV-2 vaccine Influenza (Flu) vaccine Symptom Research in context Evidence before this study The PubMed database was searched for articles published form 01/12/2020 until 29/09/2022, with search criteria: “((Long COVID) OR (post-acute) OR (post-COVID) OR (ongoing-symptoms)) AND (vaccination) AND (symptoms)”, yielding 320 articles.
A flowchart of the study design is presented in Fig. 1. Schematic representation of the study. The figure describes the links between dietary intake and the studied vitamin A-related metabolites, and highlights the research questions we are addressing, the data, and the analytical workflow used The descriptive characteristics of the study populations are presented in Table 1.
Research in context Evidence before the study We searched PubMed for articles published up to Dec 20, 2021, using the terms “vaccine effectiveness waning” or “vaccine booster” and “COVID-19”. We found reviews summarising that titres of binding and neutralising antibodies wane over time for all vaccines and that this is also applicable to COVID-19 vaccines.
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