Abstract Background: Knee osteoarthritis (KOA) involves interactions among whole-joint loading, tissue mechanics, and cellular responses. This study mapped the structure and temporal evolution of KOA biomechanics research using bibliometric analysis and machine-learning-assisted topic modeling. Methods: English-language articles and reviews published from 2005 to 2025 were retrieved from the Web of Science Core Collection and Scopus, merged, deduplicated, and screened.
