Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description smll76143-sup-0001-SuppMat.docx7.9 MB Supporting File: smll76143-sup-0001-SuppMat.docx.