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A. Iribarne on Muck Rack

A. Iribarne

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Modulating SPARC expression in mesenchymal stem cells improves MSCs-mediated skin regeneration and wound repair

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By A. V. Lombardi, M. García Verified, A. Waisman, J. Smucler, M. B. Palma, A. Iribarne, A. La Greca, L. N. Moro, G. E. Sevlever, S. G. Miriuka, C. D. Luzzani
| Nature Verified
Abstract Mesenchymal stem cells (MSCs) have garnered significant attention over the past three decades due to their robust regenerative potential, primarily mediated through their paracrine activity, involving the release of soluble bioactive factors and extracellular vesicles (EVs). The MSC secretome plays a pivotal role in wound healing by influencing cellular migration, inflammation, angiogenesis, extracellular matrix (ECM) remodeling, and re-epithelialization.
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