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A. Mark Evans

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Articles by A. Mark Evans

A modified Delphi consensus on creating a time-clocked care pathway in severe asthma – time is of the essence

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By D. Price, GW Canonica, A. Mark Evans, S. A. Patel, M. Bhutani, T. Winders, M. Kupczyk, JWH Kocks
| Nature Verified
Abstract Severe asthma (SA) affects approximately 10% of the global asthma population. Symptoms and exacerbations lead to reduced quality of life and increased hospitalisations. Patients with uncontrolled disease often experience increased risks due to delays in referral, assessment, and treatment initiation. The aim of this study was to establish multinational consensus on the preferred approach to time-clocked care in the management of SA from primary through to specialist care.
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Human embryonic stem cell-derived dopaminergic cells for Parkinson’s disease: a phase 1/2 open-label trial

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By G. S. Paul, R. F. Smith, A. Mark Evans, B. Harry, E. Cutting, O. Hansson, M. K. B. Parmar, R. A. Barker, H. Bjartmarz, A. Kirkeby, J. Nelander, S. Kayhanian, S. Fazal, N. P. Lao-Kaim, T. van Vliet, S. Ullén, I. Grubor, P. Piccini, O. Lindvall, A. Björklund, H. Widner
| Nature Verified
Abstract Parkinson’s disease (PD) is characterized by progressive loss of nigral dopaminergic neurons, resulting in disabling motor symptoms. Intracerebral transplantation of stem cell-derived dopaminergic progenitors to replace lost endogenous dopaminergic neurons offers a new potentially restorative therapeutic approach for PD.
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Four ppm measurement of the antihydrogen ground-state hyperfine splitting

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By C. Baker, W. Bertsche, N. Bhatt, G. Bonomi, A. Capra, I. Carli, C. L. Cesar, M. B. Charlton, A. Cridland Mathad, D. Duque Quiceno, S. Eriksson, A. Mark Evans, J. Fajans, T. Max Friesen, M. Fujiwara, L. Golino, M. Gonçalves, J. S. Hangst, D. Hodgkinson, C. Isaac, S. A. Jones, S. Jonsell, N. M. Madsen, V. R. Marshall, T. Momose, J. Nauta, A. Oliveira, A. Powell, C. Rasmussen, T. Robertson-Brown, F. Robicheaux, J. Schoonwater, J. A. Singh, G. R. Smith, C. So, S. Stracka, J. Suh, K. Thompson, R. I. Thompson, E. Thorpe-Woods, A. Jiménez, M. Urioni, P. Woosaree, J. S. Wurtele, R. Akbari, L. O. de Araujo Azevedo, A. Del Vincio, M. E. Hayden, P. Heidari, J. T. K. McKenna, R. L. Sacramento, E. Sarid, D. M. Silveira, A. G. Swadling, T. D. Tharp, D. P. van de Werf, S. G. Wilson
| Nature Verified
Abstract The hydrogen atom is a touchstone for the foundations, evolution and frontiers of quantum theory1,2,3,4,5,6,7,8,9. Key spectral lines of this atom have been determined to remarkable precision10,11. Our research focuses on the study of antihydrogen, the antimatter counterpart of hydrogen. We test fundamental symmetries of nature (such as simultaneous charge conjugation, parity inversion, and time reversal or CPT symmetry) through precision comparisons of these atomic systems12.
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AMPK deficiency in smooth muscles causes persistent pulmonary hypertension of the new-born and premature death - Nature Communications

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By Javier Moral-Sanz, Sandy MacMillan, Benoit Viollet, Marc Foretz, A. Mark Evans
| Nature Verified
Abstract AMPK has been reported to facilitate hypoxic pulmonary vasoconstriction but, paradoxically, its deficiency precipitates pulmonary hypertension. Here we show that AMPK-α1/α2 deficiency in smooth muscles promotes persistent pulmonary hypertension of the new-born.
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